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Office of Behavioral & Social Sciences Research
National Institutes of Health
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Setting the Scene
Appropriate Research Methods
'Science' in the Social Sciences
Design Decisions in Research
Theory Development
Social and Behavioral Theories
Describing How
Sample Surveys
Social Survey Data Collection
Administrative Data Systems
Observational Studies
Explaining Why
Qualitative Methods
Conversation Analysis
Software and Qualitative Analysis
What Works
Clinical Trials
Cluster Unit Randomized Trials
Emerging Issues
Ethical Challenges
Multilevel Modeling
Objective Measurement of Subjective Phenomena
Measuring Socioeconomic Status
Evaluating the Quality of Health Care
Patient-Reported Outcomes
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Setting the Scene
Appropriate Research Methods
'Science' in the Social Sciences
Design Decisions in Research
Theory Development
Social and Behavioral Theories
Describing How
Sample Surveys
Social Survey Data Collection
Administrative Data Systems
Observational Studies
Explaining Why
Qualitative Methods
Conversation Analysis
Software and Qualitative Analysis
What Works
Clinical Trials
Cluster Unit Randomized Trials
Emerging Issues
Ethical Challenges
Multilevel Modeling
Objective Measurement of Subjective Phenomena
Measuring Socioeconomic Status
Evaluating the Quality of Health Care
Patient-Reported Outcomes
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This Chapter
Contents
Cluster Unit Randomized Trials
1. Learning Objectives
2. Introduction
3. Statistical Implications
4. Common Designs
5. Pair-Matching
6. Unit of Inference
7. Sample Size Assessment
8. Factors Influencing Power
9. Cluster Level Replication
10. CRTs and Informed Consent
11. Cluster vs. Individual Level Analysis
12. Perils of Subsampling
13. Other Perils
14. Analyses at the Individual Level
15. Interim Analyses
16. Cohort vs. Cross-sectional Designs
17. Reporting
18. Appendix
19. Summary
20. References
21. Author Biography
This Chapter
Contents
Appropriate Research Methods
'Science' in the Social Sciences
Design Decisions in Research
Theory Development
Social and Behavioral Theories
Sample Surveys
Social Survey Data Collection
Administrative Data Systems
Observational Studies
Qualitative Methods
Conversation Analysis
Software and Qualitative Analysis
Clinical Trials
Cluster Unit Randomized Trials
Ethical Challenges
Multilevel Modeling
Objective Measurement of Subjective Phenomena
Measuring Socioeconomic Status
Evaluating the Quality of Health Care
Patient-Reported Outcomes
Tables
Figures
Exercises
Examples
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Cluster Unit Randomized Trials
2. Introduction
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