Rid and Wendler’s Guidance for Risk/Benefit Assessment
- The research is scientifically sound so that valuable knowledge may result
- The proposed intervention(s) are necessary to achieving the research goals.
- Evaluate the risk of harm to subjects on the basis of existing data and subject characteristics.
- Evaluate the probability and magnitude of possible benefits to subjects on the basis of existing data and subject characteristics.
- Evaluate whether research benefits outweigh risks or vice versa on the basis of data and best judgment.
- Assess whether risks are justified by potential benefits using available data and expert experience.
- Evaluate whether risks are justified by the potential value of the research (Rid & Wendler, 2011).