Clinical Trials

2. Introductions

Exercise 3

Which study design would potentially need the most patients?

  • Equivalence study
  • Superiority study
  • Non-inferiority study

Answers:

  • Equivalence study [Yes! Equivalence study is based on two-sided statistical test and therefore needs more patients.]
  • Superiority study [No. Superiority study is based on one-sided statistical test and therefore needs less patients than equivalence study.]
  • Non-inferiority study [No. Like superiority study, non-inferiority study is based on one-sided statistical test and needs less patients than equivalence study.]