Clinical Trials

4. Endpoints

Exercise 5

Which of the following is not a potential trial endpoint?

The potential endpoint are:

  • Dosage of study drug.
  • Time to disease relapse
  • Biochemical marker of disease
  • Patient’s stress level
  • Cost of patient’s care over a given time period

Answers:
Dosage of study drug.
[Correct! Dosage of study drug does not reflect efficacy or safety aspect of study drug and therefore cannot be used as an endpoint.]

Time to disease relapse
[Incorrect! Time to disease relapse is often used as an endpoint to indicate timing and occurance of disease relapse.]

Biochemical marker of disease
[Incorrect! Biochemical marker of disease is often used as a surrogate endpoint in clinical trials.]

Patient’s stress level
[Incorrect! Patient’s stress level is often used as an endpoint in stress management interventional studies.]

Cost of patient’s care over a given time period
[Incorrect! Cost of patient’s care over a given time period is often used in clinical trials to measure health economics of study drug.]